CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.630 | Aminopeptidase |
|
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
| Superfamily | Zn peptidases |
| Functional Family | Cytosolic non-specific dipeptidase |
Enzyme Information
| 3.4.13.18 |
Cytosol nonspecific dipeptidase.
based on mapping to UniProt Q9D1A2
Hydrolysis of dipeptides, preferentially hydrophobic dipeptides including prolyl amino acids.
-!- Broad specificity, varying somewhat with source species. -!- Activated and stabilized by dithiothreitol and manganese. -!- Inhibited by bestatin and leucine. -!- Belongs to peptidase family M20. -!- Formerly EC 3.4.3.1, EC 3.4.3.2, EC 3.4.3.3, EC 3.4.3.6, EC 3.4.13.1, EC 3.4.13.2, EC 3.4.13.3, EC 3.4.13.8, EC 3.4.13.11, EC 3.4.13.13 and EC 3.4.13.15.
|
UniProtKB Entries (1)
| Q9D1A2 |
CNDP2_MOUSE
Mus musculus
Cytosolic non-specific dipeptidase
|
PDB Structure
| PDB | 2ZOF |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.
J.Biol.Chem.
|
