CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.670
Functional Family

Enzyme Information

5.6.2.3
DNA topoisomerase (ATP-hydrolyzing).
based on mapping to UniProt P9WG45
ATP-dependent breakage, passage and rejoining of double-stranded DNA.
-!- The enzyme can introduce negative superhelical turns into double- stranded circular DNA. -!- One unit has nicking-closing activity, and another catalyzes super- twisting and hydrolysis of ATP (cf. EC 5.6.2.2). -!- Formerly EC 5.99.1.3.

UniProtKB Entries (1)

P9WG45
GYRB_MYCTU
Mycobacterium tuberculosis H37Rv
DNA gyrase subunit B

PDB Structure

PDB 2ZJT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of DNA gyrase B' domain sheds lights on the mechanism for T-segment navigation
Fu, G.S., Wu, J.J., Liu, W., Zhu, D.Y., Hu, Y.L., Deng, J., Zhang, X.E., Bi, L.J., Wang, D.C.
Nucleic Acids Res.