CATH Classification

Domain Context

CATH Clusters

Superfamily High mobility group box domain
Functional Family Histone-lysine N-methyltransferase

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt Q8NEZ4
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

Q8NEZ4
KMT2C_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase 2C

PDB Structure

PDB 2YUK
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the HMG box of human Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
Abe, H., Tochio, N., Miyamoto, K., Koshiba, S., Harada, T., Watanabe, S., Kigawa, T., Yokoyama, S.
To be Published