CATH Domain 2ybpA01

Superfamily	Cupin
Functional Family	Lysine-specific demethylase 4A

1.14.11.-

With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.

based on mapping to UniProt O75164

H31T_HUMAN

Homo sapiens

Histone H3.1t

PDB	2YBP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. Chowdhury, R., Yeoh, K.K., Tian, Y.M., Hillringhaus, L., Bagg, E.A., Rose, N.R., Leung, I.K., Li, X.S., Woon, E.C., Yang, M., McDonough, M.A., King, O.N., Clifton, I.J., Klose, R.J., Claridge, T.D., Ratcliffe, P.J., Schofield, C.J., Kawamura, A. EMBO Rep.