CATH Domain 2x6iA03

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.1070	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5
	1.10.1070.11	Phosphatidylinositol 3-/4-kinase, catalytic domain

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-/4-kinase, catalytic domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q9W1M7_DROME

Drosophila melanogaster

Phosphatidylinositol 3-kinase catalytic subunit type 3

PDB Structure

PDB	2X6I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Miller, S., Tavshanjian, B., Oleksy, A., Perisic, O., Houseman, B.T., Shokat, K.M., Williams, R.L. Science