CATH Domain 2x6iA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1010	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
	3.30.1010.10	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 4
Functional Family	Phosphatidylinositol 3-kinase catalytic subunit type 3

Enzyme Information

UniProtKB Entries (1)

Q9W1M7_DROME

Drosophila melanogaster

Phosphatidylinositol 3-kinase catalytic subunit type 3

PDB Structure

PDB	2X6I
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34. Miller, S., Tavshanjian, B., Oleksy, A., Perisic, O., Houseman, B.T., Shokat, K.M., Williams, R.L. Science