CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Non-specific serine/threonine protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9Y243
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9Y243
AKT3_HUMAN
Homo sapiens
RAC-gamma serine/threonine-protein kinase

PDB Structure

PDB 2X18
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of the Ph Domain of Human Akt3 Protein Kinase
Vollmar, M., Wang, J., Zhang, Y., Elkins, J.M., Burgess-Brown, N., Chaikuad, A., Pike, A.C.W., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S.
To be Published