CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.575 | P1 Nuclease |
|
1.10.575.10 | P1 Nuclease |
Domain Context
CATH Clusters
| Superfamily | P1 Nuclease |
| Functional Family | Phospholipase C |
Enzyme Information
| 3.1.4.3 |
Phospholipase C.
based on mapping to UniProt Q0TV31
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.
|
UniProtKB Entries (1)
| Q0TV31 |
PHLC_CLOP1
Clostridium perfringens ATCC 13124
Phospholipase C
|
PDB Structure
| PDB | 2WXT |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Comparison of a Nontoxic Variant of Clostridium Perfringens [Alpha]-Toxin with the Toxic Wild-Type Strain
Acta Crystallogr.,Sect.D
|