CATH Classification

Domain Context

CATH Clusters

Superfamily Dehydroquinase, class II
Functional Family

Enzyme Information

4.2.1.10
3-dehydroquinate dehydratase.
based on mapping to UniProt Q48255
3-dehydroquinate = 3-dehydroshikimate + H(2)O.

UniProtKB Entries (1)

Q48255
AROQ_HELPY
Helicobacter pylori 26695
3-dehydroquinate dehydratase

PDB Structure

PDB 2WKS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
Prazeres, V.F., Tizon, L., Otero, J.M., Guardado-Calvo, P., Llamas-Saiz, A.L., van Raaij, M.J., Castedo, L., Lamb, H., Hawkins, A.R., Gonzalez-Bello, C.
J. Med. Chem.