CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Macrocin O-methyltransferase |
Enzyme Information
| 2.1.1.285 |
Demethyldecarbamoylnovobiocin O-methyltransferase.
based on mapping to UniProt Q9L9F2
S-adenosyl-L-methionine + demethyldecarbamoylnovobiocin = S-adenosyl-L- homocysteine + decarbamoylnovobiocin.
-!- The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic novobiocin.
|
UniProtKB Entries (1)
| Q9L9F2 |
NOVP_STRNV
Streptomyces niveus
Demethyldecarbamoylnovobiocin O-methyltransferase
|
PDB Structure
| PDB | 2WK1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal Structure of the Novobiocin Biosynthetic Enzyme Novp: The First Representative Structure for the Tylf O-Methyltransferase Superfamily.
J.Mol.Biol.
|
