CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.540 | Fructose-1,6-Bisphosphatase; Chain A, domain 1 |
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3.30.540.10 | Fructose-1,6-Bisphosphatase, subunit A, domain 1 |
Domain Context
CATH Clusters
Superfamily | Fructose-1,6-Bisphosphatase, subunit A, domain 1 |
Functional Family | Fructose-1,6-bisphosphatase 1 |
Enzyme Information
3.1.3.11 |
Fructose-bisphosphatase.
based on mapping to UniProt P09467
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.
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UniProtKB Entries (1)
P09467 |
F16P1_HUMAN
Homo sapiens
Fructose-1,6-bisphosphatase 1
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PDB Structure
PDB | 2WBB |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Sulfonylureido Thiazoles as Fructose-1,6-Bisphosphatase Inhibitors for the Treatment of Type-2 Diabetes.
Bioorg.Med.Chem.Lett.
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