CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.940 | Eukaryotic RPB6 RNA polymerase subunit | |
3.90.940.20 | RPB5-like RNA polymerase subunit |
Domain Context
CATH Clusters
Superfamily | RPB5-like RNA polymerase subunit |
Functional Family |
Enzyme Information
2.7.7.6 |
DNA-directed RNA polymerase.
based on mapping to UniProt B8YB60
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.
|
UniProtKB Entries (1)
B8YB60 |
B8YB60_SACSH
Saccharolobus shibatae B12
DNA-directed RNA polymerase subunit H
|
PDB Structure
PDB | 2WB1 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Evolution of Complex RNA Polymerase: The Complete Archaeal RNA Polymerase Structure
Plos Biol.
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