CATH Domain 2w4lF00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.140	Cytidine Deaminase; domain 2
	3.40.140.10	Cytidine Deaminase, domain 2

Domain Context

CATH Clusters

Superfamily	Cytidine Deaminase, domain 2
Functional Family	Deoxycytidylate deaminase

Enzyme Information

3.5.4.12

dCMP deaminase.

based on mapping to UniProt P32321

dCMP + H(2)O = dUMP + NH(3).

-!- Also acts on some 5-substituted dCMPs.

UniProtKB Entries (1)

DCTD_HUMAN

Homo sapiens

Deoxycytidylate deaminase

PDB Structure

PDB	2W4L
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Crystal Structure of Human Dcmp Deaminase Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schuler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Nordlund, P. To be Published