CATH Classification

Domain Context

CATH Clusters

Superfamily Carbon-nitrogen hydrolase
Functional Family Nitrilase family member 2

Enzyme Information

3.5.1.3
Omega-amidase.
based on mapping to UniProt Q9JHW2
A monoamide of a dicarboxylate + H(2)O = a dicarboxylate + NH(3).
-!- Acts on glutaramate, succinamate and their 2-oxo derivatives.

UniProtKB Entries (1)

Q9JHW2
NIT2_MOUSE
Mus musculus
Omega-amidase NIT2

PDB Structure

PDB 2W1V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Functional Proteomic and Structural Insights Into Molecular Recognition in the Nitrilase Family Enzymes.
Barglow, K.T., Saikatendu, K.S., Bracey, M.H., Huey, R., Morris, G.M., Olson, A.J., Stevens, R.C., Cravatt, B.F.
Biochemistry
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