CATH Domain 2vzpA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.120	Jelly Rolls
	2.60.120.260	Galactose-binding domain-like

Domain Context

CATH Clusters

Superfamily	Galactose-binding domain-like
Functional Family	Exo-beta-D-glucosaminidase

Enzyme Information

3.2.1.165

Exo-1,4-beta-D-glucosaminidase.

based on mapping to UniProt Q56F26

Hydrolysis of chitosan or chitosan oligosaccharides to remove successive D-glucosamine residues from the non-reducing termini.

-!- Chitosan is a partially or totally N-deacetylated chitin derivative that is found in the cell walls of some phytopathogenic fungi and comprises D-glucosamine residues with a variable content of GlcNAc residues. -!- Acts specifically on chitooligosaccharides and chitosan, having maximal activity on chitotetraose, chitopentaose and their corresponding alcohols. -!- Can degrade GlcN-GlcNAc but not GlcNAc-GlcNAc.

UniProtKB Entries (1)

Q56F26

EBDG_AMYOR

Amycolatopsis orientalis

Exo-beta-D-glucosaminidase

PDB Structure

PDB	2VZP
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function. Montanier, C., Van Bueren, A.L., Dumon, C., Flint, J.E., Correia, M.A., Prates, J.A., Firbank, S.J., Lewis, R.J., Grondin, G.G., Ghinet, M.G., Gloster, T.M., Herve, C., Knox, J.P., Talbot, B.G., Turkenburg, J.P., Kerovuo, J., Brzezinski, R., Fontes, C.M.G.A., Davies, G.J., Boraston, A.B., Gilbert, H.J. Proc.Natl.Acad.Sci.USA