CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.140 | Metal-dependent hydrolases |
Domain Context
CATH Clusters
| Superfamily | Metal-dependent hydrolases |
| Functional Family | Enamidase |
Enzyme Information
| 3.5.2.18 |
Enamidase.
based on mapping to UniProt Q0QLE9
6-oxo-1,4,5,6-tetrahydronicotinate + 2 H(2)O = 2-formylglutarate + NH(3).
-!- Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.
|
UniProtKB Entries (1)
| Q0QLE9 |
ENA_EUBBA
Eubacterium barkeri
Enamidase
|
PDB Structure
| PDB | 2VUN |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal Structure of Enamidase: A Bifunctional Enzyme of the Nicotinate Catabolism.
J.Mol.Biol.
|
