CATH Classification

Domain Context

CATH Clusters

Superfamily Urease, subunit C, domain 1
Functional Family Enamidase

Enzyme Information

3.5.2.18
Enamidase.
based on mapping to UniProt Q0QLE9
6-oxo-1,4,5,6-tetrahydronicotinate + 2 H(2)O = 2-formylglutarate + NH(3).
-!- Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.

UniProtKB Entries (1)

Q0QLE9
ENA_EUBBA
Eubacterium barkeri
Enamidase

PDB Structure

PDB 2VUN
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of Enamidase: A Bifunctional Enzyme of the Nicotinate Catabolism.
Kress, D., Alhapel, A., Pierik, A.J., Essen, L.-O.
J.Mol.Biol.