CATH Domain 2vunD01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.40	Urease, subunit C; domain 1
	2.30.40.10	Urease, subunit C, domain 1

Domain Context

CATH Clusters

Superfamily	Urease, subunit C, domain 1
Functional Family	Enamidase

Enzyme Information

3.5.2.18

Enamidase.

based on mapping to UniProt Q0QLE9

6-oxo-1,4,5,6-tetrahydronicotinate + 2 H(2)O = 2-formylglutarate + NH(3).

-!- Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. -!- Other enzymes involved in this pathway are EC 1.17.1.5, EC 1.3.7.1, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6, EC 4.2.1.85 and EC 4.1.3.32.

UniProtKB Entries (1)

Q0QLE9

ENA_EUBBA

Eubacterium barkeri

Enamidase

PDB Structure

PDB	2VUN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Crystal Structure of Enamidase: A Bifunctional Enzyme of the Nicotinate Catabolism. Kress, D., Alhapel, A., Pierik, A.J., Essen, L.-O. J.Mol.Biol.