CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.90 | Alpha-Beta Complex | |
3.90.226 | 2-enoyl-CoA Hydratase; Chain A, domain 1 | |
3.90.226.10 | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Domain Context
CATH Clusters
Superfamily | 2-enoyl-CoA Hydratase; Chain A, domain 1 |
Functional Family | p-hydroxycinnamoyl CoA hydratase/lyase |
Enzyme Information
4.2.1.101 |
Trans-feruloyl-CoA hydratase.
based on mapping to UniProt O69762
4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA = feruloyl-CoA + H(2)O.
|
4.1.2.41 |
Vanillin synthase.
based on mapping to UniProt O69762
3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = vanillin + acetyl- CoA.
-!- Involved, together with EC 4.2.1.101 in the production of vanillin from trans-ferulic acid. -!- Vanillin is converted to vanillate by EC 1.2.1.67.
|
UniProtKB Entries (1)
O69762 |
HCHL_PSEFL
Pseudomonas fluorescens
Hydroxycinnamoyl-CoA hydratase-lyase
|
PDB Structure
PDB | 2VSU |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A Ternary Complex of Hydroxycinnamoyl-Coa Hydratase-Lyase (Hchl) with Acetyl-Coa and Vanillin Gives Insights Into Substrate Specificity and Mechanism.
Biochem.J.
|