CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.180 | Quinone Oxidoreductase; Chain A, domain 1 |
|
3.90.180.10 | Medium-chain alcohol dehydrogenases, catalytic domain |
Domain Context
CATH Clusters
| Superfamily | Medium-chain alcohol dehydrogenases, catalytic domain |
| Functional Family | Enoyl-[acyl-carrier-protein] reductase, mitochondrial |
Enzyme Information
| 1.3.1.104 |
Enoyl-[acyl-carrier-protein] reductase.
based on mapping to UniProt Q9BV79
An acyl-[acyl-carrier protein] + NADP(+) = a trans-2,3-dehydroacyl-[acyl- carrier protein] + NADPH.
-!- The enzyme completes each cycle of fatty acid elongation by catalyzing the stereospecific reduction of the double bond at position 2 of a growing fatty acid chain, while linked to the acyl- carrier protein, in an NADPH-dependent manner. -!- This entry stands for enzymes whose stereo-specificity with respect to NADP(+) is not known (cf. EC 1.3.1.39, EC 1.3.1.10 and EC 1.3.1.9).
|
UniProtKB Entries (1)
| Q9BV79 |
MECR_HUMAN
Homo sapiens
Enoyl-[acyl-carrier-protein] reductase, mitochondrial
|
PDB Structure
| PDB | 2VCY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Enzymological Studies of 2-Enoyl Thioester Reductase of the Human Mitochondrial Fas II Pathway: New Insights Into its Substrate Recognition Properties.
J.Mol.Biol.
|