CATH Domain 2vc7B00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.140	Metal-dependent hydrolases

Domain Context

CATH Clusters

Superfamily	Metal-dependent hydrolases
Functional Family

Enzyme Information

3.1.8.1

Aryldialkylphosphatase.

based on mapping to UniProt Q97VT7

An aryl dialkyl phosphate + H(2)O = dialkyl phosphate + an aryl alcohol.

-!- Acts on organophosphorus compounds (such as paraoxon) including esters of phosphonic and phosphinic acids. -!- Inhibited by chelating agents. -!- Previously regarded as identical with EC 3.1.1.2.

UniProtKB Entries (1)

Q97VT7

PHP_SACS2

Saccharolobus solfataricus P2

Aryldialkylphosphatase

PDB Structure

PDB	2VC7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities. Elias, M., Dupuy, J., Merone, L., Mandrich, L., Porzio, E., Moniot, S., Rochu, D., Lecomte, C., Rossi, M., Masson, P., Manco, G., Chabriere, E. J.Mol.Biol.