CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.8 | Helicase, Ruva Protein; domain 3 |
|
1.10.8.60 |
Domain Context
CATH Clusters
| Superfamily | 1.10.8.60 |
| Functional Family | DNA polymerase epsilon subunit |
Enzyme Information
| 2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P56282
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
| P56282 |
DPOE2_HUMAN
Homo sapiens
DNA polymerase epsilon subunit 2
|
PDB Structure
| PDB | 2V6Z |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
The Solution Structure of the Amino-Terminal Domain of Human DNA Polymerase Epsilon Subunit B is Homologous to C-Domains of Aaa+ Proteins.
Nucleic Acids Res.
|
