CATH Domain 2v0gA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.740	Isoleucyl-tRNA Synthetase; domain 2
	3.90.740.10	Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain

Domain Context

CATH Clusters

Superfamily	Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q7SIE4_THETH

Thermus thermophilus

Leucine--tRNA ligase

PDB Structure

PDB	2V0G
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site. Rock, F., Mao, W., Yaremchuk, A., Tukalo, M., Crepin, T., Zhou, H., Zhang, Y., Hernandez, V., Akama, T., Baker, S., Plattner, J., Shapiro, L., Martinis, S.A., Benkovic, S.J., Cusack, S., Alley, M.R.K. Science