CATH Domain 2rfhA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.630	Aminopeptidase
	3.40.630.10	Zn peptidases

Domain Context

CATH Clusters

Superfamily	Zn peptidases
Functional Family	Carboxypeptidase A1

Enzyme Information

3.4.17.1

Carboxypeptidase A.

based on mapping to UniProt P00730

Release of a C-terminal amino acid, but little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.

-!- Isolated from cattle, pig and dogfish pancreas, and other sources including mast cells and skeletal muscle. -!- Belongs to peptidase family M14. -!- Formerly EC 3.4.2.1 and EC 3.4.12.2.

UniProtKB Entries (1)

P00730

CBPA1_BOVIN

Bos taurus

Carboxypeptidase A1

PDB Structure

PDB	2RFH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A Wang, S.-H., Wang, S.-F., Xuan, W., Zeng, Z.-H., Jin, J.-Y., Ma, J., Tian, G.R. Bioorg.Med.Chem.