CATH Classification
Level | CATH Code | Description |
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3 | Alpha Beta |
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3.30 | 2-Layer Sandwich |
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3.30.70 | Alpha-Beta Plaits |
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3.30.70.270 | Reverse transcriptase/Diguanylate cyclase domain |
Domain Context
CATH Clusters
Superfamily | 3.30.70.270 |
Functional Family | DNA polymerase IV |
Enzyme Information
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q97W02
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
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UniProtKB Entries (1)
Q97W02 |
DPO4_SACS2
Saccharolobus solfataricus P2
DNA polymerase IV
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PDB Structure
PDB | 2RDJ |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Snapshots of a Y-family DNA polymerase in replication: substrate-induced conformational transitions and implications for fidelity of Dpo4.
J.Mol.Biol.
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