CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.200 | Peptidase S8/S53 domain |
Domain Context
CATH Clusters
| Superfamily | Peptidase S8/S53 domain |
| Functional Family | Proprotein convertase subtilisin/kexin type 9 |
Enzyme Information
| 3.4.21.- |
Serine endopeptidases.
based on mapping to UniProt Q8NBP7
|
UniProtKB Entries (1)
| Q8NBP7 |
PCSK9_HUMAN
Homo sapiens
Proprotein convertase subtilisin/kexin type 9
|
PDB Structure
| PDB | 2QTW |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain.
Proc.Natl.Acad.Sci.Usa
|