CATH Classification

Domain Context

CATH Clusters

Superfamily TPP-binding domain
Functional Family NAD-dependent protein deacetylase HST2

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt P53686

UniProtKB Entries (1)

P02309
H4_YEAST
Saccharomyces cerevisiae S288C
Histone H4

PDB Structure

PDB 2QQF
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis for nicotinamide inhibition and base exchange in sir2 enzymes.
Sanders, B.D., Zhao, K., Slama, J.T., Marmorstein, R.
Mol.Cell
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