CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.460 | Ferredoxin Thioredoxin Reductase |
|
3.90.460.10 | Ferredoxin thioredoxin reductase catalytic beta subunit |
Domain Context
CATH Clusters
| Superfamily | Ferredoxin thioredoxin reductase catalytic beta subunit |
| Functional Family | Ferredoxin-thioredoxin reductase, catalytic chain |
Enzyme Information
| 1.8.7.2 |
Ferredoxin:thioredoxin reductase.
based on mapping to UniProt Q55389
2 reduced ferredoxin + thioredoxin disulfide = 2 oxidized ferredoxin + thioredoxin + 2 H(+).
-!- The enzyme contains a [4Fe-4S] cluster and internal disulfide. -!- It forms a mixed disulfide with thioredoxin on one side, and docks ferredoxin on the other side, enabling two one-electron transfers. -!- The reduced thioredoxins generated by the enzyme activate the Calvin cycle enzymes EC 3.1.3.11, EC 3.1.3.37 and EC 2.7.1.19 as well as other chloroplast enzymes by disulfide reduction.
|
UniProtKB Entries (2)
| P07591 |
TRXM_SPIOL
Spinacia oleracea
Thioredoxin M-type, chloroplastic
|
| Q55389 |
FTRC_SYNY3
Synechocystis sp. PCC 6803 substr. Kazusa
Ferredoxin-thioredoxin reductase, catalytic chain
|
PDB Structure
| PDB | 2PUK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase.
Nature
|