CATH Domain 2pjtA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	Collagenase 3

Enzyme Information

3.4.24.-

Metalloendopeptidases.

based on mapping to UniProt P45452

UniProtKB Entries (1)

MMP13_HUMAN

Homo sapiens

Collagenase 3

PDB Structure

PDB	2PJT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure-based design of TACE selective inhibitors: manipulations in the S1'-S3' pocket. Huang, A., Joseph-McCarthy, D., Lovering, F., Sun, L., Wang, W., Xu, W., Zhu, Y., Cui, J., Zhang, Y., Levin, J.I. Bioorg.Med.Chem.