CATH Classification

Domain Context

CATH Clusters

Superfamily Metal-dependent hydrolases
Functional Family

Enzyme Information

UniProtKB Entries (1)

A5KE01
A5KE01_PLAVS
Plasmodium vivax Sal-1
Adenosine deaminase, putative

PDB Structure

PDB 2PGR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity.
Larson, E.T., Deng, W., Krumm, B.E., Napuli, A., Mueller, N., Van Voorhis, W.C., Buckner, F.S., Fan, E., Lauricella, A., DeTitta, G., Luft, J., Zucker, F., Hol, W.G., Verlinde, C.L., Merritt, E.A.
J.Mol.Biol.
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