CATH Classification

Domain Context

CATH Clusters

Superfamily Cysteine proteinases
Functional Family Cysteine proteinase falcipain 2a

Enzyme Information

UniProtKB Entries (2)

Q8I6U4
Q8I6U4_PLAF7
Plasmodium falciparum 3D7
Cysteine proteinase falcipain 2a
Q966X9
CHAG_TRYCR
Trypanosoma cruzi
Chagasin

PDB Structure

PDB 2OUL
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of chagasin in complex with a cysteine protease clarifies the binding mode and evolution of an inhibitor family.
Wang, S.X., Pandey, K.C., Scharfstein, J., Whisstock, J., Huang, R.K., Jacobelli, J., Fletterick, R.J., Rosenthal, P.J., Abrahamson, M., Brinen, L.S., Rossi, A., Sali, A., McKerrow, J.H.
Structure