CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic |
Enzyme Information
| 4.2.1.10 |
3-dehydroquinate dehydratase.
based on mapping to UniProt Q9SQT8
3-dehydroquinate = 3-dehydroshikimate + H(2)O.
|
| 1.1.1.25 |
Shikimate dehydrogenase.
based on mapping to UniProt Q9SQT8
Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.
-!- NAD(+) cannot replace NADP(+). -!- In higher organisms, this enzyme forms part of a multienzyme complex with EC 4.2.1.10.
|
UniProtKB Entries (1)
| Q9SQT8 |
DHQSD_ARATH
Arabidopsis thaliana
Bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase, chloroplastic
|
PDB Structure
| PDB | 2O7S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The DHQ-dehydroshikimate-SDH-shikimate-NADP(H) Complex: Insights into Metabolite Transfer in the Shikimate Pathway
Cryst.Growth Des.
|
