CATH Domain 2nylC00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.21	Purple Acid Phosphatase; chain A, domain 2
	3.60.21.10	Metallo-dependent phosphatases

Domain Context

CATH Clusters

Superfamily	3.60.21.10
Functional Family	Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16

Protein-serine/threonine phosphatase.

based on mapping to UniProt P67775

[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.

-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

Q13362

2A5G_HUMAN

Homo sapiens

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

PDB Structure

PDB	2NYL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of the Protein Phosphatase 2A Holoenzyme. Xu, Y., Xing, Y., Chen, Y., Chao, Y., Lin, Z., Fan, E., Yu, J.W., Strack, S., Jeffrey, P.D., Shi, Y. Cell(Cambridge,Mass.)