CATH Classification

Domain Context

CATH Clusters

Superfamily Inosine monophosphate cyclohydrolase-like
Functional Family

Enzyme Information

3.5.4.10
IMP cyclohydrolase.
based on mapping to UniProt O27099
IMP + H(2)O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.

UniProtKB Entries (1)

O27099
PURO_METTH
Methanothermobacter thermautotrophicus str. Delta H
IMP cyclohydrolase

PDB Structure

PDB 2NTL
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A novel function for the N-terminal nucleophile hydrolase fold demonstrated by the structure of an archaeal inosine monophosphate cyclohydrolase.
Kang, Y.N., Tran, A., White, R.H., Ealick, S.E.
Biochemistry