CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1270.220
Functional Family bromodomain-containing protein 2 isoform X1

Enzyme Information

UniProtKB Entries (2)

Q8UN00
Q8UN00_MLVMO
Moloney murine leukemia virus
Pr180 Gag-Pro-Pol polyprotein
O60885
BRD4_HUMAN
Homo sapiens
Bromodomain-containing protein 4

PDB Structure

PDB 2N3K
External Links
Method SOLUTION NMR
Organism
Primary Citation
Structure of the Brd4 ET domain bound to a C-terminal motif from gamma-retroviral integrases reveals a conserved mechanism of interaction.
Crowe, B.L., Larue, R.C., Yuan, C., Hess, S., Kvaratskhelia, M., Foster, M.P.
Proc.Natl.Acad.Sci.USA