CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.20 | Ubiquitin-like (UB roll) |
|
3.10.20.90 | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 |
| Functional Family | Serine/threonine-protein kinase WNK1 isoform 1 |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9JIH7
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (1)
| Q9JIH7 |
WNK1_RAT
Rattus norvegicus
Serine/threonine-protein kinase WNK1
|
PDB Structure
| PDB | 2LRU |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution Structure of the WNK1 Autoinhibitory Domain, a WNK-Specific PF2 Domain.
J.Mol.Biol.
|