CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 |
|
1.20.58.870 |
Domain Context
CATH Clusters
| Superfamily | 1.20.58.870 |
| Functional Family | DNA helicase |
Enzyme Information
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt Q14566
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| Q14566 |
MCM6_HUMAN
Homo sapiens
DNA replication licensing factor MCM6
|
PDB Structure
| PDB | 2LE8 |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Structural insights into the Cdt1-mediated MCM2-7 chromatin loading
Nucleic Acids Res.
|