CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family L-lactate dehydrogenase

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt P00344
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

P00344
LDH_GEOSE
Geobacillus stearothermophilus
L-lactate dehydrogenase

PDB Structure

PDB 2LDB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure determination and refinement of Bacillus stearothermophilus lactate dehydrogenase.
Piontek, K., Chakrabarti, P., Schar, H.P., Rossmann, M.G., Zuber, H.
Proteins