CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Tyrosine-protein kinase

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt P16591
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P16591
FER_HUMAN
Homo sapiens
Tyrosine-protein kinase Fer

PDB Structure

PDB 2KK6
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of sh2 domain of proto-oncogene tyrosine-protein kinase fer from homo sapiens, northeast structural genomics consortium (nesg) target hr3461d
Tang, Y., Montelione, G.T.
To be Published