CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.30 | Glutaredoxin |
|
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
| Superfamily | Glutaredoxin |
| Functional Family | thioredoxin domain-containing protein 12 |
Enzyme Information
| 1.8.4.2 |
Protein-disulfide reductase (glutathione).
based on mapping to UniProt O95881
2 glutathione + protein-disulfide = glutathione disulfide + protein- dithiol.
-!- Reduces insulin and some other proteins.
|
UniProtKB Entries (1)
| O95881 |
TXD12_HUMAN
Homo sapiens
Thioredoxin domain-containing protein 12
|
PDB Structure
| PDB | 2K8V |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase .
Biochemistry
|
