CATH Classification

Domain Context

CATH Clusters

Superfamily 2.20.70.10
Functional Family Phosphorylated CTD-interacting factor 1

Enzyme Information

2.1.1.62
mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase.
based on mapping to UniProt Q9H4Z3
S-adenosyl-L-methionine + a 5-(N(7)-methyl 5-triphosphoguanosine)-2'-O- methyladenosine-[mRNA] = S-adenosyl-L-homocysteine + a 5-(N(7)-methyl 5-triphosphoguanosine)-N(6),2'-O-dimethyladenosine-[mRNA].
-!- mRNA containing an N(6),2'-O-dimethyladenosine cap.

UniProtKB Entries (1)

Q9H4Z3
CAPAM_HUMAN
Homo sapiens
MRNA (2'-O-methyladenosine-N(6)-)-methyltransferase

PDB Structure

PDB 2JX8
External Links
Method SOLUTION NMR
Organism
Primary Citation
1H, 13C, and 15N resonance assignments of hPCIF1 WW domain
Kouno, T., Iwamoto, Y., Hirose, Y., Aizawa, T., Demura, M., Kawano, K., Ohkuma, Y., Mizuguchi, M.
To be Published
CATH-Gene3D is a Global Biodata Core Resource Learn more...