CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | 23S rRNA (Uracil(1939)-C(5))-methyltransferase RlmD |
Enzyme Information
| 2.1.1.35 |
tRNA (uracil(54)-C(5))-methyltransferase.
based on mapping to UniProt Q9UZR7
S-adenosyl-L-methionine + uracil(54) in tRNA = S-adenosyl-L-homocysteine + 5-methyluracil(54) in tRNA.
-!- Unlike this enzyme, EC 2.1.1.74 uses 5,10-methylenetetrahydrofolate and FADH(2) to supply the atoms for methylation of U54.
|
UniProtKB Entries (1)
| Q9UZR7 |
ATRMA_PYRAB
Pyrococcus abyssi GE5
TRNA (uracil(54)-C(5))-methyltransferase
|
PDB Structure
| PDB | 2JJQ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal Structure of Pyrococcus Abyssi tRNA (Uracil-54, C5)-Methyltransferase Provides Insights Into its tRNA Specificity.
Nucleic Acids Res.
|