CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | Probable 4-aminobutyrate aminotransferase |
Enzyme Information
| 2.6.1.36 |
L-lysine 6-transaminase.
based on mapping to UniProt P9WQ77
L-lysine + 2-oxoglutarate = (S)-2-amino-6-oxohexanoate + L-glutamate.
-!- The product, (S)-2-amino-6-oxohexanoate, is converted into the intramolecularly dehydrated form, 1-piperideine 6-carboxylate.
|
UniProtKB Entries (1)
| P9WQ77 |
LAT_MYCTU
Mycobacterium tuberculosis H37Rv
Probable L-lysine-epsilon aminotransferase
|
PDB Structure
| PDB | 2JJG |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mutational Analysis of Mycobacterium Tuberculosis Lysine Epsilon-Aminotransferase and Inhibitor Co-Crystal Structures, Reveals Distinct Binding Modes.
Biochem.Biophys.Res.Commun.
|
