1 keywords

CATH Domain 2jisB02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.640 Aspartate Aminotransferase; domain 2
Homologous Superfamily 3.40.640.10 Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Glutamate decarboxylase like 1

Enzyme Information

4.1.1.11
Aspartate 1-decarboxylase.
based on mapping to UniProt Q9Y600
L-aspartate = beta-alanine + CO(2).
4.1.1.29
Sulfinoalanine decarboxylase.
based on mapping to UniProt Q9Y600
3-sulfino-L-alanine = hypotaurine + CO(2).
-!- Also acts on L-cysteate.

UniProtKB Entries (1)

Q9Y600
CSAD_HUMAN
Homo sapiens
Cysteine sulfinic acid decarboxylase

PDB Structure

PDB 2JIS
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of Human Cysteine Sulfinic Acid Decarboxylase (Csad)
Collins, R., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Holmberg-Schiavone, L.
To be Published