CATH Domain 2j8sA04

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.2090	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
	3.30.2090.10	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains

Domain Context

CATH Clusters

Superfamily	Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
Functional Family	Efflux pump membrane transporter

Enzyme Information

UniProtKB Entries (1)

ACRB_ECOLI

Escherichia coli K-12

Multidrug efflux pump subunit AcrB

PDB Structure

PDB	2J8S
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Drug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors. Sennhauser, G., Amstutz, P., Briand, C., Storchenegger, O., Grutter, M.G. Plos Biol.