CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Probable tyrosine-protein phosphatase

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P40479
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P40479
SDP1_YEAST
Saccharomyces cerevisiae S288C
Dual-specificity protein phosphatase SDP1

PDB Structure

PDB 2J17
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases.
Fox, G.C., Shafiq, M., Briggs, D.C., Knowles, P.P., Collister, M., Didmon, M.J., Makrantoni, V., Dickinson, R.J., Hanrahan, S., Totty, N., Stark, M.J., Keyse, S.M., McDonald, N.Q.
Nature
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