CATH Classification

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family Cyclin-A2

Enzyme Information

UniProtKB Entries (1)

P24941
CDK2_HUMAN
Homo sapiens
Cyclin-dependent kinase 2

PDB Structure

PDB 2I40
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase
Bamborough, P., Christopher, J.A., Cutler, G.J., Dickson, M.C., Mellor, G.W., Morey, J.V., Patel, C.B., Shewchuk, L.M.
Bioorg.Med.Chem.Lett.
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