CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.850 | Fumarylacetoacetate hydrolase; domain 2 |
|
3.90.850.10 | Fumarylacetoacetase-like, C-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Fumarylacetoacetase-like, C-terminal domain |
| Functional Family | Fumarylacetoacetase |
Enzyme Information
| 3.7.1.2 |
Fumarylacetoacetase.
based on mapping to UniProt P35505
4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate.
-!- Also acts on other 3,5- and 2,4-dioxo acids.
|
UniProtKB Entries (1)
| P35505 |
FAAA_MOUSE
Mus musculus
Fumarylacetoacetase
|
PDB Structure
| PDB | 2HZY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Biochem.J.
|
