CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.30 | SH3 type barrels. |
|
2.30.30.230 | Fumarylacetoacetase, N-terminal domain |
Domain Context
CATH Clusters
| Superfamily | Fumarylacetoacetase, N-terminal domain |
| Functional Family | Fumarylacetoacetase |
Enzyme Information
| 3.7.1.2 |
Fumarylacetoacetase.
based on mapping to UniProt P35505
4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate.
-!- Also acts on other 3,5- and 2,4-dioxo acids.
|
UniProtKB Entries (1)
| P35505 |
FAAA_MOUSE
Mus musculus
Fumarylacetoacetase
|
PDB Structure
| PDB | 2HZY |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Biochem.J.
|
