CATH Classification

Domain Context

CATH Clusters

Superfamily 2-enoyl-CoA Hydratase; Chain A, domain 1
Functional Family Enoyl-CoA hydratase, mitochondrial

Enzyme Information

4.2.1.17
Enoyl-CoA hydratase.
based on mapping to UniProt P30084
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
-!- Acts in the reverse direction. -!- With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).

UniProtKB Entries (1)

P30084
ECHM_HUMAN
Homo sapiens
Enoyl-CoA hydratase, mitochondrial

PDB Structure

PDB 2HW5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of human enoyl-coenzyme A (CoA) hydratase short chain 1, ECHS1
Turnbull, A.P., Salah, E., Niesen, F., Debreczeni, J., Ugochukwu, E., Pike, A.C.W., Kavanagh, K., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Oppermann, U.
To be Published