CATH Domain 2hjeA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.450	Beta-Lactamase
	3.30.450.220	LuxQ periplasmic domain, N-terminal subdomain

Domain Context

CATH Clusters

Superfamily	LuxQ periplasmic domain, N-terminal subdomain
Functional Family

Enzyme Information

2.7.13.3	Histidine kinase. based on mapping to UniProt P54302 ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. -!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
3.1.3.-	Phosphoric monoester hydrolases. based on mapping to UniProt P54302

UniProtKB Entries (1)

LUXQ_VIBHA

Vibrio harveyi

Autoinducer 2 sensor kinase/phosphatase LuxQ

PDB Structure

PDB	2HJE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. Neiditch, M.B., Federle, M.J., Pompeani, A.J., Kelly, R.C., Swem, D.L., Jeffrey, P.D., Bassler, B.L., Hughson, F.M. Cell(Cambridge,Mass.)